Shreyash P's Senior Project Blog
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Project Title: Anti-Fog Strategy Via Surface Energy Engineering Using New Hyper-Hydrophilic Coatings: Model And Application to Lenses in Medical Devices BASIS Advisor: William Schaffer Internship Location: Banner Health Onsite Mentor: Professor Nicole Herbots - Emeritus Professor at ASU |
Project Abstract
During human cavity surgeries, doctors use a thin, tube-like camera (an endoscope) to see inside the body. However, these cameras can easily fog up due to many reasons – difference in temperature causes humidity or moisture from the patient’s body. When the camera fogs, surgeons have to repeatedly pull it out to clean it, which can increase the risk of infection, contamination, surgery time, and extra scar tissue. In the past, other anti-fog coatings –FRED and Clearify – either didn’t last long enough or took too long to dry, leading surgeons to clean the camera lens often. Our solution is to create a medical device ClearEndoscope™ that holds the improved gel KnoxFog™ without needing a separate drying step. We are looking to create a solution that in one apply can prevent fogging for over two hours. ClearEndoscope™ is a ready-to-use applicator device that holds the anti-fog gel, KnoxFog™.. This gel has “hyper-hydrophilic” properties, meaning it pulls water droplets into a thin layer, flattening the water droplets that form on the lens and preventing elliptical distortion. Once this product is finalized and made available, it could benefit hospitals worldwide – especially in areas with fewer resources – by reducing the times surgeons have to remove, clean, and reinsert the camera, in turn helping to lower risks of infection and scarring. This research has applications outside of the medical field with preventative commercial uses for windshields, glasses, lenses, etc.
Conclusion; Goodbye Everyone!
Final Week Reflection As I wrap up my time working on the KnoxFog™ project, I want to sincerely thank those who made this experience so impactful. To Professor Herbots - thank you for your unwavering guidance and for believing in the potential of undergraduate research. Your dedication to scientific truth and mentorship has inspired me... Read More
Week 10: Wrapping Up & Looking Ahead
Hi everyone! This week has been a whirlwind as we near the end of the project. Most of my time has been spent in the lab working to gather the shareable prototype of KnoxFog™ to bring in for my presenation. While the process has been exciting, recently, my professor and research team also encountered some... Read More
Week 9: Clarity, Coatings, and Closing Loops
Welcome back to the final weeks of the ClearEndoscope™ and KnoxFog™ blog series! Over the past nine weeks, we've journeyed through the inner workings of our biomedical engineering project— from ideation to experimentation (all the complicated theory) , and from materials science to molecular magic. This week we will sum up everything and talk about... Read More
Week 8: Lets go Back in Time….
Welcome back to our weekly ClearEndoscope™ and KnoxFog™ blog series! This week, we’re taking a step back—not in progress, but in physics. We're diving deep into the science of why fogging even happens in the first place. By understanding the role of surface energy and water condensation, we’re uncovering the very principles that guide the... Read More
Week 7: One-Step Applicator Refinements & Next Steps in Animal Testing
Welcome back to our weekly series on ClearEndoscope™ and KnoxFog™ progress! If you recall from Week 6, we introduced our newly simplified, single-compartment silicone applicator and shared our excitement about its successful first animal trial on a pig. This week, we’ll dive into further tweaks to the applicator design, lessons learned from continuing testing, and... Read More
Week 6: Streamlining the Applicator & First Animal Trial
Welcome back, everyone! This week, I’m excited to share some key updates on the ClearEndoscope™ applicator design and our first round of animal testing. Before we get into the details, here’s a quick five-question quiz to review concepts from last time and set the stage for this week’s progress. Week 6 Quiz What was the... Read More
Week 5: The Doctor Will See You Now…
Welcome back to my research blog! This week marks a major milestone for the KnoxFog™ project as I wrap up data analysis from our three core experiments and turn my attention to how we’ll implement these findings in real-world surgical settings. If you’ve been following along, you know we’ve compared KnoxFog™ to both uncoated lenses... Read More
Week 4: Let the Trials Begin…
Hello Everyone and welcome to week 4 of my research on KnoxFog - the anti-fog solution that will revolutionize closed-cavity surgeries! This last week has been eventful, I have continued my work on analyzing the data we have from our tests and am currently working on publishing the teams findings to a conference for publication... Read More
Week 3: Comparative Anti-Fog Trials, Experiment Design, and Surgical Insights
Hello everyone, and welcome to Week 3 of my blog series on KnoxFog™ - the hyper-hydrophilic, semi-solid anti-fog gel designed to improve visualization in endoscopic procedures. The last couple weeks have been long as I was on vacation and just came back from the senior trip. We all had a great time! :) This week,... Read More
Week 2: Advancing KnoxFog™ – Prototype Development and Application Optimization
Welcome back to my research blog! This past week has been full of exciting developments as I continue understanding the KnoxFog™ coating for its application in medical devices, particularly in endoscopic surgery. While I have been working on datat analysis, I want to catch you all up on: Enhancing the durability of KnoxFog™ for prolonged... Read More
Week 1: An Introduction to Fogging and the Evolution of Anti-Fog Tech
Early Testing and Progress on KnoxFog™ Welcome back to week 2 of my research blog! As I dive deeper into my senior research project, I wanted to share an update on the early testing of KnoxFog™ and the progress made in optimizing this novel anti-fog coating for medical applications. Over the next few few weeks,... Read More
Welcome to My Senior Research Project: Engineering a Fog-Free Future to Medical Surgeries
Hi everyone, and welcome to my research blog! My name is Shreyash Prakash, and over the next few months, I’ll be diving deep into an exciting project at the intersection of materials science and biomedical technology. My senior research project, titled: Anti-Fog Strategy Via Surface Energy Engineering Using New Hyper-Hydrophilic Coatings: Model and Application to... Read More