Week 6: Gels and Beads

Claire S -

This week, I went into the lab on Thursday and got to help out on two projects. The first project was about the diets of large carnivores like pumas and bobcats. I got to run a gel electrophoresis to see if the PCR step worked out. My mentor wanted to know what size fragments had been amplified. We made a solution of 1% agarose and then poured it into the container and let it harden. We prepared the DNA by adding a dye which makes it easier to see under the UV light. We very carefully pipetted the DNA into each of the wells. The next step involved hooking the gel up to the machine that would run 100 volts through the gel. We let it run and then placed it on a UV light and took a picture of the gel. (Pictures at the end)

The other project I helped with involved Songbird samples. We extracted the DNA from dried blood samples and I got to use a bead beater machine. We put plastic beads inside the tubes and the machine spun them really fast. We used a different protocol than Qiagen but it was mostly the same. (Pictures at the end).

Other than that, I researched more about the Sidewinder rattlesnakes and worked on editing my proposal. Our sequencing data came back which I will hopefully be able to look at next week once some paperwork is done.  That’s all I did this week; I got my wisdom teeth out last week so I wanted to take things easy.

Me pipetting the DNA into one of the wells
The results of our gel
Before we used the bead beater
After we used the bead beater

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Comments:

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    Charlotte
    Hi Claire! It's so cool that you're getting to work on many different projects in the lab! I found it interesting that you used plastic beads in the bead beater because at my lab it looks like we use steel beads. Do you know if there's a reason for using plastic over other types of beads? Also, I hope your wisdom teeth surgery went well. It's so funny how everyone in our blog group seems to be getting their wisdom teeth out!
    Kristen Sanders
    These pictures are great! Keep 'em coming! Also, I hope your wisdom teeth removal went well. Everyone seems to be getting them out this trimester!
    Sophia DiPonio
    Hi Claire! I really appreciated getting to see some pictures of your work, they’re so cool! I hope that getting your wisdom teeth removed wasn’t too bad! I agree with Charlotte and Ms. Sanders, it’s funny how everyone is getting their wisdom teeth out this trimester!
    azumi_v
    Hey Claire! So cool you got to work on two different projects. I'm also recovering from my wisdom teeth removal haha best of luck with that!
    telsi_c
    Hey Claire! Looks like you had a pretty eventful week, balancing some awesome projects while recovering from your wisdom teeth removal. Welcome to the club!!!! Can’t wait to hear more once that sequencing data comes through.
    claire_s
    Hi Charlotte! It's interesting that you used steel beads! I don't know if you reused your beads; if not, maybe it's just because of the cost.

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