Madison D's Senior Project Blog
| 
						
						 | 
					
						 Project Title: UNcertain and UNsafe: How United Nations Legislation Could Combat Global Biotechnological Weapons Development BASIS Advisor: Holly Sow Internship Location: Arizona State University Onsite Mentor: Dr. Dave Engelthaler  | 
				
Project Abstract
In 2012, Vladimir Putin predicted that nuclear and chemical weapons would, in the near future, be eclipsed by a new warfare giant: genetic science (Biberman, 1). Biotechnologies like CRISPR, a DNA editing tool, are being developed in labs all across the world today, renowned for their potential to secure a healthier tomorrow for humankind. But how can we trust science’s intentions? The very cutting-edge studies that revolutionize healthcare are the blueprints for new forms of biological weaponry should they fall into the wrong hands. In 1975, the United Nations passed the Biological Weapons Convention (BWC) for this exact reason. With slow revision methods and gridlocked committees, though, the legislation arguably lacks the mechanisms to effectively control emerging biotechnological threats. Further, many countries oppose regulation because it limits a healthy dissemination of groundbreaking medical information. Working with Dr. David Engelthaler at the Health Observatory at ASU, I consult experts in biotechnology, genomic science and health law. In discussions, I focus on learning about emerging biotechnologies and regulation mechanisms that facilitate a safer, more certain era of public safety. I plan to discover the manner in which biotechnology is regulated both within the scientific community and by lawmakers. With this project, I hope to center specifics that the BWC lacks, such as the way biotechnologies like CRISPR can be appropriately managed in order to maintain global cooperation while still regulating pressing threats to public health, and I plan to propose potential modifications to the BWC that account for biotechnological advancements happening right now. Biberman, Yelena. “The Technologies and International Politics of Genetic Warfare.” Strategic Studies Quarterly 15, no. 3 (2021) https://www.airuniversity.af.edu/10/SSQ/Biberman."
Week 11: Certain and Safe
Hello everyone! This week 11 blog post marks the end of the senior project journey for 2025. I’ve finished my powerpoint and my proposal document and am pretty much planning to revise and practice both until they’re burned into my retinas. Special thanks to everyone who’s commented on my blogs, seniors and freshman alike. I’ve... Read More
Week 10: AL/EG
Hello everyone! We’re getting close to the end of this project so I thought I would show you the final proposal I’ve been working on. I just finished this yesterday so bear with me, it’s my first draft. Anyways, the idea was that I would separate my ideas into categories, and then further subdivide those... Read More
Week 9: Red Teaming
Hello! This week I had a conversation with Rachel Levinson, the Executive Director of National Research Initiatives for ASU. She talked a lot about the future danger of AI in terms of biosecurity, namely in the creation of new real life organisms from code on a computer. That capability isn’t something we’re necessarily looking at... Read More
Week 8: Party On!
Hello everyone! This week I wanted to talk about a super interesting conversation I had with Dr. George Poste. Dr. Poste is an incredibly impressive academic and scientist and it was really insightful to hear his opinion on some of the facets of my project (he was even given the rank of Commander of the... Read More
Week 7: Ad Hoc
Hi everyone! This week we’re going to get into one of the solutions I’m looking at for my final presentation for my project (I currently have three that I’m planning on presenting alongside a few others that others in my research have suggested). In case you forgot, the goal of my project is to find... Read More
Week 6: Ethical Asymmetry & Designer Babies
Hello! Just coming off of spring break I’ve mostly been trying to organize all of my notes into categories so I can work better towards my project goal. With that being said, this week I wanted to talk a little bit about ethical asymmetry since it’s kind of the logical continuation of NAPs and how... Read More
Week 5: Spring Break
Hello! No updates this week because of spring break. Fortunately, though, in the coming weeks, I’ll be able to meet my site placement in person and do more than just converse digitally (ASU has rules about volunteers/visitors who are minors). I look forward to updating next week. Have a nice break! Read More
Week 4: Do You Need a NAP?
Hello! Today is exciting because I get to tell you about the Biological Weapons Convention (BWC). The last time I mentioned the BWC was Week 1, so, after some much needed focus on biotech, I think it’s about time to talk about the actual treaty we’re looking at. The BWC, signed in 1972, ratified in... Read More
Week 3: CRISPR-GPT, Biohacking & Other Things You Probably Shouldn’t Do in Your Basement
Welcome back! Last week we focused a bit on CRISPR and its applications. Now, I want to look towards what CRISPR looks like in reality. Who can actually use it? What are they using it for? How are they using it? Answering these questions will help me to figure out how (or if) it can... Read More
Week 2: Clustered Regularly Interspaced Short Palindromic Repeats
Hello everyone! Today, we’re going to be focusing on genome editing, specifically a system known as CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats). CRISPR actually has a pretty interesting history and was discovered initially as a naturally occurring part of bacteria immune systems. To put it simply, CRISPR operates using two parts: a Cas enzyme... Read More
Week 1: The Issue With Dual-Use Biotech
Welcome back! Last time, we talked briefly about why the BWC is ineffective in its intended purpose. It’s still early in the project, so most of what I’ve done is independent research on the BWC and on biotechnology. That’s why, for this blog post, I want to go a little more in depth on what... Read More
Week 0: A Plan to Make a Plan to Make a Plan
Most of us, after watching documentaries and sitting through our history classes, are familiar with images of gas masks in WWI. Chemical and biological warfare have stained government hands across the world, spanning both world wars and beyond. Their use has been widely condemned–the Geneva Protocol signed in 1925 says so itself. This treaty aimed... Read More
